Anti-diabetic activity of Thespesia lampas Dalz & Gibs on alloxan induced rats

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Antioxidant and Anti-Lipoxygenase Activity of Thespesia lampas Dalz & Gibs

Antioxidant activities and Anti-inflammatory activity of the extracts were evaluated by a 1, 1-diphenyl, 2-picrylhydrazyl free radical (DPPH), 2, 2’-Azinobis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and antilipoxygenase assay for the water extraction of Thespesia lampas Dalz & Gibs. Ascorbic acid, gallic acid and indomethacin were used as reference standards for DPPH, ABTS and anti-lipox...

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Hepatoprotective and antioxidant activity of Thespesia lampas (Cav.) Dalz & Gibs

Thespesia lampas (Cav.) Dalz & Gibs an important folk medicinal plant was evaluated for hepatoprotective and antioxidant activity against carbon tetrachloride (CCl4) induced hepatic damage in rats. In the present study, the T. lampas stems extracts at dose of 200 mg/kg body wt. were administered orally once daily for nine days and on seventh day after one hour of drug administration CCl4 (1ml/k...

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Anti-Diabetic Activity of Terminalia catappa Linn. Leaf Extracts in Alloxan-Induced Diabetic Rats

In view of suggested anti diabetic potential, effect of aqueous and cold extracts of Terminalia Catappa Linn (Combretaceae) leaves, on fasting blood sugar levels and serum biochemical analysis in alloxan-induced diabetic rats was investigated. All the extracts of Terminalia Catappa produced a significant anti diabetic activity at dose levels of 1/5th of their lethal doses. Concurrent histologic...

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Antidiabetic Activity of Polyherbal Extract on Alloxan Induced Diabetic Rats

Polyherbal extract which consists of ethanolic extract of MadhucaLatifolia, AristolochiaBracteata, AristolochiaIndica was investigated for its possible antidiabetic effect in alloxan-induced diabetic rats and to assess the synergistic activity of three plants. The animals were grouped into four six animals each. The first group received normal saline solution(0.9% sodium chloride), which was us...

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Attenuation of Diabetic Nephropathy by Carvacrol through Anti-oxidative Effects in Alloxan-Induced Diabetic Rats

Background and Objectives: Diabetes, a common metabolic disorder, is prevalent in many countries. Nephropathy is a main debate’s side effect. Role of oxidative stress is well known in induction of diabetic nephropathy while carvacrol is a potent anti-oxidant that might attenuate oxidative stress. The aim of this study was to explore the effect of carvacrol in d...

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ژورنال

عنوان ژورنال: Oriental Pharmacy and Experimental Medicine

سال: 2008

ISSN: 1598-2386

DOI: 10.3742/opem.2008.8.4.349